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This can result in sarcopenic obesity , particularly in older or frail populations, and raises new questions about treatment sustainability
It modulates metabolic pathways, including pyruvate dehydrogenase activity, proteolysis, and protein synthesis, while also having anti-inflammatory and antioxidant characteristics
9,14,15 Potential benefits and limitations of cycle-synchronized eating A 2024 systematic review of 28 experimental studies reported that targeted nutritional interventions - including vitamin D, calcium, magnesium, zinc, and curcumin - were frequently associated with reductions in menstrual-related symptoms such as pain and fatigue, though study quality, intervention dosage, and outcome measures varied substantially
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Additionally, mRNA expression levels of RUNX-2 and ALP, two key osteogenic markers, were found to be 1.6- and 1.8-fold higher, respectively, in differentiated cells compared to undifferentiated controls
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