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Ethics declarations Conflict of Interest James Amamoo: Employee of Novo Nordisk Inc

In this answer 4 sections Based on current medical evidence, there is no proof that GLP-1 medications like Ozempic or Wegovy cause permanent or irreversible gastroparesis [1] [2]

More serious but rare adverse effects can include pancreatitis, gallbladder problems (particularly with rapid weight loss), thyroid-related issues, and in people with type 2 diabetes using semaglutide, potential worsening of diabetic retinopathy

A 2022 study of over 300 people participants, people lost an average of 17.3% of their starting weight taking 2.4mg semaglutide (Wegovy) for 68 weeks

10.13192/j.issn.1000-1719.2023.03.034 47 FuF.LuoH.DuY.ChenY.TianK.PanJ.et al (2023)