Disentangling the relationship between chronic kidney disease and cognitive disorders
Patients underwent a 9 week run-in period (3-week forced dose escalation followed by a 6-week dose maintenance phase) with rosiglitazone (starting at 4 mg and increasing to 8 mg/day within 2 weeks) and metformin (starting at 500 mg with increasing weekly increments of 500 mg to a final dose of 2,000 mg/day)
Modi ME, Connor-Stroud F, Landgraf R, Young LJ, Parr LA (2014)
Dazu kann man aktuell keine Aussagen treffen, da es noch keine serise Forschung zur kurz- und langfristigen Wirkung von Kleinstdosierungen gibt
The FDA has approved its use for chronic weight management in adults with a body mass index (BMI) of 30 or more, or a BMI of 27 or more when accompanied by at least one weight-related condition such as high blood pressure, high cholesterol, or type 2 diabetes