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In this GLP-1 round up: Oral GLP-1 delivers up to 12.4% weight loss in Phase III trial, offering injection-free alternative High-dose semaglutide achieves 25%+ weight loss in one-third of patients without added safety concerns FDA provides regulatory clarity for muscle-preserving drugs to break through the weight loss plateau WHO issues first recommendation for GLP-1s in obesity, framing it as chronic disease requiring long-term treatment Table of Contents New Drug Formulations and Clinical Trial Data Orforglipron: Phase III Data for Oral GLP-1 Eli Lillys orforglipron, an oral GLP-1 receptor agonist, reported Phase III results from the ATTAIN-1 trial in the New England Journal of Medicine

These medications reduce hepatic glucose production, enhance insulin secretion, limit glucose absorption, and improve peripheral glucose utilization (9)

Its mechanism involves increasing lipid peroxidation and decreasing ferroptosis markers in these cells ( Ginsenoside Rh3 has proven effective in eliminating colorectal cancer (CRC) cells

An update on the effects of vitamin D on the Immune System and Autoimmune diseases

Vitamin C together with Alpha Lipoic Acid (ALA) serves as added whitening agents in advanced skin brightening formulations