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En los individuos con DM2, este efecto incretina est alterado, siendo hasta un 25 % menor 21

Why GLP-1 Matters for Metabolic Health GLP-1 supports metabolic health through several key actions: Stimulates insulin release when blood glucose rises Reduces excess glucagon production, helping prevent blood sugar spikes Slows gastric emptying, which improves post-meal glucose control Promotes feelings of fullness and satiety Supports long-term insulin sensitivity These combined effects help stabilize blood sugar, reduce metabolic stress, and support overall cardiometabolic resilience

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The release medium consisted of 200 mL Sorensens phosphate buffer (pH 5.5) with 0.01% v/v Tween 80, maintained at 37 0.5 C under stirring at 200 rpm