Atli M, Engin-Ustun Y, Tokmak A, Caydere M, Hucunenoglu S, Topcuoglu C
Sarah Jones Simmer, CEO of Found, said in an interview with Fierce Healthcare that the trends are likely the result of irresponsible prescribing for recreational reasons causing the pendulum to swing "all the way in the other direction," and it's leading to patients who have genuine medical need struggling to access these therapies
Paw withdrawal threshold was calculated from the average of two trials, using SemmesWeinstein von Frey monofilaments with bending forces of 0.008, 0.02, 0.04, 0.07, 0.16, 0.4, 0.6, and 1.0 g) applied in ascending order to the plantar surface
Once-weekly subcutaneous injection Compounded by state-licensed pharmacies Average 1215% body weight reduction at 12 months in published trials No insurance required shipping doctors doctor 24/7 Same price at every dose
This makes it a focus in research on fundamental cellular processes rather than just acute energy provision