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Given the critical role of GLS in cancer metabolism and tumor progression, inhibiting GLS and targeting its breakdown have emerged as promising strategies for cancer treatment

STEP 4 (Rubino et al., JAMA 2021) addressed the maintenance question: after 20 weeks of semaglutide run-in (during which participants lost a mean of 10.6% of body weight), those randomized to continue semaglutide for 48 more weeks lost an additional 7.9%, while those switched to placebo regained 6.9%

Yet, I've had bouts of nausea with each of these medicines I tried

Eat small, frequent, nutrient-dense meals to maintain steady blood sugar and calorie intakeskipping meals or under-eating during the adjustment phase intensifies tiredness

Trisporus [81] or supplementation with a mixture of L