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But apart from its action on insulin, GIP is also believed to improve the bodys long-term lipid storage, such that it reduces fat accumulation in the skeletal muscles and organs.14 This dual activity is likely what accounts for tirzepatides superlative efficacy for weight loss in clinical studies

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Generalizability of glucagon-like peptide-1 receptor agonist cardiovascular outcome trials to the overall type 2 diabetes population in the United States

676 Antikainen, A

In patients without CKD, exenatide was associated with a numerically lower incidence of this outcome (RR 0.87, 95% CI 0.741.02