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Bitarafan et al, 76 reported that consuming a vitamin A (retinyl palmitate) dose of 2500 IU daily within six months continued by 10.000 IU per day for another six months, significantly improved depression scales in patients with multiple sclerosis

In the review, the researchers discovered that older adults had a higher prevalence of gastrointestinal adverse events when taking anti-obesity medications

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However, both compounds individually cause: Nausea (60-80% of users at higher doses) Vomiting (20-35%) Diarrhea (25-40%) Injection site reactions (15-25%) Potential pancreatitis (rare but serious) Combining these compounds could theoretically amplify these effects, though the actual incidence and severity remain unstudied