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Accordingly, current European Society of Cardiology (ESC) guidelines [28] for the management of patients with chronic coronary syndrome recommend GLP-1 RA for those with type 2 diabetes mellitus (class I, level A) and the GLP-1 RA semaglutide for those without diabetes mellitus when being overweight (BMI 27kg/m 2 ) or obese (class IIa, level B)

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