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GLP- 1 receptor agonism has not been thoroughly studied, but it has been demonstrated in certain cell lines to activate additional G-protein subunits and alternative downstream signaling pathways [60,61,62] GIP Receptor Signaling The mature 42 amino acid GIP attaches itself to the b cell surface and activates its cognate receptor, the GIP receptor

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Asterisks indicate significant difference (P0.05) from control values, # indicate significant difference (P0.05) from 5 mol/ml ASA treated group and indicate significant difference (P0.05) as compared to 10 mol/ml ASA treated group

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