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CoQ10 primarily functions within mitochondria, but it can also be found in various other subcellular organelles, including the endoplasmic reticulum, Golgi, lysosome, and peroxisome
These segments bear the most mechanical stress during daily activities, making them particularly vulnerable to injury and degeneration
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Activation of the glucagon-like peptide-1 receptor (GLP-1R) potentiates the exchange protein directly activated by cyclic adenosine monophosphate/phosphoinositide 3-kinase/protein kinase B (Epac/PI3K/Akt), cyclic adenosine monophosphate/protein kinase A (cAMP/PKA), and adenosine monophosphate-activated protein kinase/sirtuin 1 (AMPK/SIRT1) pathways, which enhance mitochondrial function, autophagy, and metabolic reprogramming
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