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Tissue samples All samples were processed at the Department of Pathology, Landspitali National University Hospital, Reykjavik, Iceland

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7.2 mmHg (semaglutide) Diastolic BP: Reduced by 5.8 mmHg vs

This effect of RRM1 silencing on erastin2-induced ferroptosis was specific: RRM1 silencing did not inhibit cell death in response to several mechanistically distinct small molecule inducers of apoptosis or other forms of non-apoptotic cell death that are not directly linked to intracellular GSH metabolism (Ko et al, 2019) (Fig S4A)