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The hydrophobic core accommodates hydrophobic drugs via noncovalent interactions, whereas the hydrophilic shell can be chemically modified with responsive groups for controlled or targeted release (225)

After 4 days of treatment, GLP-1 monotherapy and GLP-1MK-801 displayed comparable benefits on glucose tolerance relative to vehicle treatment or treatment with MK-801 (Fig

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Prevalence of polymorphisms in thiopurine metabolism and association with adverse outcomes: a South Asian region-specific systematic review and meta-analysis