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Vitiligo: A comprehensive overview Part II: Treatment options and approach to treatment. J Am Acad Dermatol

Through the production of NADPH the erythrocytes reduce the oxidative glutathione to reduced glutathione which process is catalyzed by the glutathione reductase enzyme which is a flavoprotein with FAD (flavin adenin dinucleotic)

25 A more recent Cochrane review of the pharmacologic treatment of low back pain (also not specific to lumbar spinal stenosis) found that NSAIDs, muscle relaxants, and opioids had a small effect on pain reduction, but use of muscle relaxants and opioids was complicated by a significant risk of adverse effects

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