According to the MHRA-approved product information, nausea is very common, occurring in more than 1 in 10 patients
Serious Warning Signs If you experience any of the following, you should stop taking naproxen and contact a healthcare provider immediately: Severe abdominal pain that does not go away Dark, tarry, or bloody stools (a sign of potential GI bleeding) Persistent vomiting or the inability to keep fluids down A significant decrease in urine output or dark-colored urine Note: If you have a history of stomach ulcers, kidney disease, or are taking blood thinners like warfarin (Jantoven), you must consult your doctor before taking naproxen with any GLP-1 medication

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Tirzepatide works on two different hormone systems instead of just one
Gastrointestinal issues were more common side effects in the Wegovy group, and included nausea, diarrhea, constipation, and vomiting