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Inclusion and exclusion criteria, as well as methods for treatment, have been described (58)

Additionally, IL-6 deficiency blocks this pathway, demonstrating that Akkermansia induces GLP-1 secretion via the IL-6-P9 axis and that Lactobacillus can regulate bile acid secretion and increase GLP-1 secretion via the bile acid receptor FXR/TGR5 pathway (82)

Those include the shots Zepbound and Wegovy made by Eli Lilly and Novo Nordisk, respectively and Foundayo, Eli Lilly's answer to the Wegovy pill

Some studies suggest temporary suppression of endogenous growth hormone production with prolonged use, though this effect appears reversible upon discontinuation

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