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This regulatory action leads to a reduction in the activity of aging-related -galactosidase and the expression of p16INK4A and p21, which are key mediators of the aging signal in podocytes following DM injury [104]

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ChenRRFanXHChenGZengGWXueYGLiuXTet alIrisin attenuates angiotensin II-induced cardiac fibrosis via Nrf2 mediated inhibition of ROS/ TGFbeta1/Smad2/3 signaling axis

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Neurosci Res Commun 1997