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As well as incorporating growth factors and drug compounds into biomaterials, more recent studies are beginning to introduce other compounds such as antibiotics and antioxidants (Kim et al., 2004

Oxidized LDL (oxLDL), angiotensin-II, hyperglycemia, and hypoxia can increase mtROS, leading to eNOS degradation and reduced NO synthesis and secretion [151, 152]

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angiotensin IV analogue Sequence (formal name): N-hexanoic-Tyr-Ile-(6) aminohexanoic amide IUPAC name: 6-[(2S,3S)-2-[(2S)-2-hexanamido-3-(4-hydroxyphenyl)propanamido]-3-methylpentanamido]hexanamide Synonyms: PNB-0408, Hexanoyl-Tyr-Ile-Ahx-NH 2 , MM-201 (older designation) CAS Number: 1401708-83-5 Molecular Formula: C 27 H 44 N 4 O 5 Molecular Weight: 504.66 g/mol Solubility: slightly soluble in DMSO and methanol