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Unlike synthetic forms of B12, methylcobalamin is a naturally active form that the body can use immediately, no conversion needed

Truong B, Allegri G, Liu XB, Burke KE, Zhu X, Cederbaum SD, Hberle J, Martini PGV, Lipshutz GS (2019) Lipid nanoparticle-targeted mRNA therapy as a treatment for the inherited metabolic liver disorder arginase deficiency

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It is sometimes prescribed to treat insomnia because of its sedative properties