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According to the included studies, lycopene may show high promise in the management of digestive precancerous lesions, such as relieving mouth opening and burning sensation of oral submucous fibrosis (OSF), presenting potentially equivalent efficacy on managing oral lichen planus (OLP) as steroids and alleviating gastrointestinal precancers symptoms, meanwhile lowering colon cancer risk

doi: 10.1038/nm1202-792 128 Hanifi-MoghaddamPKapplerSSeisslerJMuller-ScholzeSMartinSRoepBOet al

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Navarro-Cruz et al., 2017)