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Satellite Cell Activation and Sequential IGF-1 Isoform Switching The MGF hypothesis proposes that MGF is first expressed to activate quiescent satellite cells, driving their proliferation while inhibiting premature differentiation before declining to allow IGF-1Ea-mediated differentiation and myotube formation

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Additionally, HER2 can be translocated to the mitochondria by the intercourse with mitochondrial heat shock protein-70 (mtHSP70), which negatively controls oxygen consumption and thus enhancing glycolysis (219)