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To test the possible increase in potency of the two drugs when given simultaneously, we injected a total volume of 4 ml of combined doses of L838,417 and CLP257 in a fixed dose ratio of \([{\mathrm{L 838,417]/[{\mathrm{CLP 257]\) = 1:55, given the relative EC50s of the two drugs calculated from the respective dose response curves with a priori assumption on the collapse at high doses of L838,417 (Fig
Abbreviations GLP-1RA: Glucagon-Like Peptide-1 Receptor Agonists SGLT2: Sodiumglucose cotransporter 2 DPP4: Dipeptidyl Peptidase-4 T2D: Type 2 diabetes AF/Aflutter: Atrial fibrillation or flutter TSH: Thyroid-stimulating hormone MPR: Medication possession ratio PS: Propensity score IPCW: Inverse probability censoring weight SMD: Standardized mean differences References McCoy RG, Herrin J, Swarna KS, Deng Y, Kent DM, Ross JS, et al
