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"Ligand-dependent interaction of estrogen receptor-alpha with members of the forkhead transcription factor family"

Step 2: Warm the medication

It regulates neuronal growth (CREB/BDNF), anti-apoptosis (BAX/Bcl-2), neuronal differentiation (pAkt, MAP2, GAP43, and AGBL4), and neuronal glucose homeostasis (GLUT1, GLUT3, and GLUT4), thereby alleviating neurodegeneration

Studies demonstrate that BAs attenuate lipopolysaccharide (LPS)-induced upregulation of NLRP3, ASC, and Caspase-1, thereby reducing MPO activity, inhibit neutrophil infiltration, and alleviate inflammatory responses ( Figure 2 )