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Severe or u003ca href=u0022 target=u0022_blanku0022 rel=u0022noopeneru0022u003eChronic Kidney u003c/au003eu003ca href=u0022 target=u0022_blanku0022 rel=u0022noopeneru0022u003eDiseaseu003c/au003e similarly extends detection times by reducing clearance, often requiring dose adjustments

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However, the medication is currently in phase 3 clinical trials to determine its long-term safety profile

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Composite cardiovascular events were defined as the first occurrence of unstable angina, myocardial infarction, revascularization (i.e., including PCI, coronary artery bypass, and stenting)