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About us Complete the enquiry form on our Contact Us page Send an email: [email protected] Call us on: +31 20 808 4414 (EU) +1 646 381 0675 (US) +61 28 417 2910 (AUS) Others Available medicines Medicine approval The respective national and regional agencies, such as the Food and Drugs Administration (FDA) in the USA or the European Medical Authority (EMA) for the European Union assess these applications and make a decision on whether to approve new medicines

Heres what the clinical data shows: Most Common: Nausea (affecting 15-44% of users), diarrhea (10-30%), vomiting (7-25%), and constipation (6-24%) Severity: 98.1% of gastrointestinal side effects are mild or moderate, with 99.5% being non-serious Duration: Median duration is 8 days for nausea, 3 days for diarrhea, and 2 days for vomiting Timing: Most side effects occur during initial weeks and dose escalation, declining over time Discontinuation: Only 4.3-10% of users discontinue therapy due to side effects Serious Events: Rare, with no increased risk of pancreatitis or malignancy in clinical trials Management: Slow dose titration, dietary modifications, and hydration significantly reduce symptoms Important Note: Weight loss is NOT caused by side effects

(STEP-1 trial)

A small, clear plastic container works well