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Guennewih B, Bitar M, Obiorah I, Hanks J, OBrien EA, Kaczorowski DC, et al

Gut microbiota specific signatures are related to the successful rate of bariatric surgery

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doi: 10.1016/S0306-4522(00)00216-5 40 EchelardY.EpsteinD

Although a prior cohort study did not show a statistically significant reduction in major cardiovascular events among patients with no previous history of cardiovascular disease [148], a meta-analysis of eight clinical trials evaluating the effect of GLP-1R agonists on cardiovascular outcomes reported a 14% reduction in major adverse cardiovascular events, with no significant heterogeneity across GLP-1R agonists or subgroups, including patients with or without previous cardiovascular disease [149]