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In our study, we demonstrated a persistent senescent-inflammatory microenvironment and a p53-serine 15 phosphorylation regulatory mechanism in keloids, which may play crucial roles in the aggression and recurrence of keloids

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However, the rapid urbanization of this area has challenged traditional construction models and conventional spatial layouts, leading to issues in rural construction such as the uncritical adoption of urban design principles, the abandonment of traditional spaces, and the erosion of local building techniques

The ideal way to do this is to talk to a healthcare professional