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Shao X, Somlo S, Igarashi P

Through the Fenton reaction, Fe + facilitates the conversion of hydrogen peroxide into highly reactive hydroxyl radicals and other ROS ( 2.1.1 Regional iron accumulation Significant alterations in iron distribution and accumulation occur in PD patient brains, a fact confirmed by postmortem studies and advanced neuroimaging techniques

* Repeated supratherapeutic ingestion(RSTI) Defined as multiple ingestions during a period greater than 24 hours *

The tissue-repair literature also extends conceptually toward nerve and other tissue types