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Valproic acid disables the Nrf2 anti-oxidant response in acute myeloid leukaemia cells enhancing reactive oxygen species-mediated killing

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Moreover, PPAR agonists activate Dickkopf-1 (DKK1) activity to decrease the canonical WNT/-catenin pathway and then inhibit fibroblast differentiation 122

[DOI] [PubMed] [Google Scholar] 48.Putz Z., Tordai D., Hajd N., Vgi O.E., Kempler M., Bkeffy M., Krei A.E., Istenes I., Horvth V., Stoian A.P., et al