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As mentioned previously, exposure to light during the biological night can suppress melatonin production, and it is also associated to a deleterious effect on health (i.e., increased risk of cancer in most epidemiology studies in night shift workers) (70, 73)

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SUBSTITUTE SHEETS (RULE 26) Claims We Claim Claim 1: A process for producing Arg 34 GLP-l (9-37) peptide comprising the steps of: a) culturing a host cell comprising a nucleotide sequence encoding of Formula (II) under suitable conditions for expression, Insoluble tag Fusion tag Arg 34 GLP-l (9-37) Formula (II) wherein, insoluble tag is a nucleotide sequence of Alanine- Valine