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Substrates for furin cleavage possess a specific 20-residue recognition sequence motif, which includes: pro- parathyroid hormone (PTH), transforming growth factor (TGF)-1 precursor, pro - albumin , membrane type-1 matrix metalloproteinase (MMP), -subunit of pro- nerve growth factor , and von Willebrand factor 337

In fact, the federal government's Dietary Guidelines for Americans suggest that people older than age 50 take a multivitamin supplement as a way to ensure adequate B12 intake

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doi: 10.1128/mBio.02210-15 155 DuDTangWZhouCSunXWeiZZhongJet al

doi: 10.3390/ijms23158629 45 LeiboSPSongsasenN