In May 2024, as second study in the New England Journal of Medicine found that the risk of a primary heart or kidney event was 24% lower in the semaglutide group
Additional concerns regarding cardiovascular effects, gallbladder disease, and potential long-term impacts on growth and development underscore the need for cautious interpretation of existing data in adolescents
Moreover, the clinical use of GLP-1RA may be finite due to the different adverse consequences, such as GIT disturbance, diarrhea, and administration site (sc) reaction, but sometimes abdominal pain, headache, and injection area (sc) reaction are also noticed during the treatment of GLP-2RA
however, the ideal medication concentration and dosage schedule have not yet been established
Beyond its anti-oxidative properties, glutathione is pivotal in metabolic processes and the synthesis and repair of DNA