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Trials of tirzepatide in obesity and type 2 diabetes have shown improvements in blood pressure, cholesterol, and HbA1c (a marker of blood sugar control) alongside weight loss, though the SURMOUNT-MMO data will be the clearest evidence on cardiovascular outcomes

Lim EL, Hollingsworth KG, Aribisala BS, Chen MJ, Mathers JC, Taylor R

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Tirzepatide has documented improvements in blood pressure, lipids, and other cardiometabolic parameters across its phase 3 program, consistent with its degree of weight loss, and cardiovascular outcome data continue to accumulate

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