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Collectively, these findings position GLP-1 and GIP receptor agonists not just as anti-diabetic or weight-loss medications, but as comprehensive metabolic therapies with potential benefits spanning multiple organ systems

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The downside of citrus peel extracts (that prevents our goodie rating) is that they usually contain some amount of essential oil components, though the amount is probably way too low to worry about unless you're super-duper sensitive

Additionally, insulin secretion is directly activated by incretin hormones (GLP-1 and GIP) via islet -cell receptors [23]