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In contrast, a constant 50 M exposure of quinone (B) overwhelms blood and cytosolic GSH and Cys, showing no signs of recovery after a 10-hour time-span

Generalized , linear , and mixed models , 2nd Edition

Mitochondria contain 1015% of the intracellular GSH reaching a concentration of 1012 mM (54) while in the cytosol the concentration is 7 mM (54, 56)

It is shallow, so the needle only travels a short distance, and it has fewer pain-sensitive nerves than deeper tissue, so most people feel a small pinch rather than a deep ache

This overlap is better understood within a broader framework of polyautoimmunity: autoimmune thyroid disease is one of the most frequent components of overt or latent polyautoimmunity, while CD may also appear within autoimmune polyendocrine or polyautoimmune clusters