Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist cotadutide via modulating mitochondrial function and lipogenesis
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3 Epidemiology Nearly 1% of the adult population is treated with GCs, with the frequency increasing up to 2.5% among patients between 70 and 79 years of age ( SIH occurs most frequently in patients receiving steroid therapy for respiratory diseases, with a reported prevalence of 22% ( 4 Role of GLP-1 receptor agonist therapy in SID Recently, GLP-1RAs have become an important class of drugs in the management of T2DM, as they significantly lower fasting plasma glucose
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A later study led by Martin Friedrichsen, also in Diabetes, Obesity and Metabolism, confirmed similar effects with the 2.4 mg dose used for weight management, showing better "control of eating" scores and reduced cravings overall (Friedrichsen et al., 2021)