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When assessing WL post-bariatric surgery and WR thereafter before initiation of therapy, our analysis found no significant differences between the GLP-1RAs and placebo groups, with (SMD = 0.23, 95% CI 0.36 to 0.81) for WL and SMD = 0.33, 95% CI 0.11 to 0.77) for WR, respectively (Supplementary Figs

These values were used to calculate the secretion rate as the concentration in the assay (ng/ml for insulin and glucagon, and pmol/mL for cAMP) times the volume of KRB in each well during the assay (0.2 mL) divided by the assay time (60 min)

Data were analysed using FlowJo (v9) software