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Why Oral Bioavailability Is Lower Even though BPC-157 survives gastric acid better than most peptides, oral administration still subjects it to: First-pass metabolism the liver processes a significant portion before it reaches systemic circulation Variable absorption affected by food, stomach pH, and individual GI function Enzymatic degradation some breakdown still occurs in the intestinal tract The result is that oral BPC-157 delivers a lower and less predictable systemic dose compared to injection
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Research demonstrates that GHK-Cu stimulation of collagen synthesis begins at concentrations between 10 and 10 M and maximizes at 10 M, with effects independent of changes in cell proliferation, indicating direct activation of synthetic machinery rather than simply increasing fibroblast numbers
This improves gland function by allowing the Meibomian gland oils to flow freely again
I was given the loading dose then prescribed 3 monthly injections which were nowhere near enogh to keep my symptoms at bay
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