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448 The NAD + biosynthesis regulated by NAMPT in adipocytes plays an important role in the pathogenesis of obesity-related metabolic complications
As with other medicines in the incretin-based therapy class, retatrutide's clinical trials have identified a range of side effects, most of which relate to its gastrointestinal activity
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The clinical manifestations include chronic pelvic pain, dysuria, progressively increasing dysmenorrhea, gastrointestinal symptoms, painful intercourse, painful bowel movements during menstruation, infertility, and irregular menstruation
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