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Although most mechanistic studies of lactylation have so far been conducted in cellular and animal models, a growing body of patient-derived data and early clinical studies has begun to underscore its translational relevance

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Moreover, the significantly higher bone volume/total volume (BV/TV) of talus bone levels after the SP@M treatment further suggested its superior performance to ameliorate the RA-induced bone degradation (Fig

"While we are disappointed to discontinue the development of danuglipron, we remain committed to evaluating and advancing promising programs in an effort to bring innovative new medicines to patients," Dr

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