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Key points All GLP-1 medications can cause musculoskeletal side effects including muscle cramps Clinical trials report 3-14% incidence of musculoskeletal symptoms depending on the medication Side effects tend to be dose-dependent and often improve with continued treatment Management approaches are similar regardless of which medication is causing the cramping Frequently asked questions How quickly do muscle cramps start after beginning Mounjaro
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Weeks 4-8 represent a critical observation window where dose adjustments often occur based on tolerance and appetite response
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