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doi:10.1371/journal.pone.0101956

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Cycle phase appears to influence energy intake, resting energy expenditure, substrate selection, and micronutrient handling, with a tendency toward higher energy intake and greater reliance on lipid oxidation during the mid-luteal phase compared with the early follicular and peri-ovulatory periods [84,171]

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A randomized controlled trial in 167 older adults (50 years) found two-year supplementation with vitamin B 12 (10 g/day), along with folic acid (200 g/day), vitamin B6 (10 mg/day), riboflavin (5 mg/day), and vitamin D (10 g/day), had no effect on bone mineral density (total hip, femoral neck, or lumbar spine) compared to the control group only receiving vitamin D (10 g/day ) (116)

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Antibiotics are essential medicines, and there are situations where their use is genuinely necessary and even life saving

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