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Arthritis Research & Therapy 17 : 245

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Metabolites that derive from the microbiota, especially SCFAs and secondary bile acids, activate G-protein-coupled receptors such as free fatty acid receptor 2 (FFAR2) and free fatty acid receptor 3 (FFAR3), as well as Takeda G-protein-coupled receptor 5 (TGR5), which are expressed by enteroendocrine L cells [115,116]

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