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MI interconverts to other inositols via an specific epimerase [13,14] that differs from the epimerase catalyzing the conversion from MI to DCI [15,16]

23 These favorable characteristics provided a rationale for testing the utility of high doses of roflumilast to prevent MTX-induced toxicity in critical organs

"Comparative study among glutamine, acetyl-L-carnitine, vitamin E and methylcobalamine for treatment of paclitaxel-induced peripheral neuropathy." Clin Cancer Investig J 3(3): 213-219

This is one reason why highly concentrated solutions are impractical for lower doses

This protocol discusses the mechanisms of acetaminophen and NSAID function and toxicity, and outlines dietary and lifestyle approaches for minimizing their toxic potential