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Am J Physiol Heart Circ Physiol Raveendran VV, Kassel KM, Smith DD, Luyendyk JP, Williams KJ, Cherian R, Reed GA, Flynn CA, Csanaky IL, Lickteig AL, Pratt-Hyatt MJ, Klaassen CD, Dileepan KN (2014b) H1-antihistamines exacerbate high-fat diet-induced hepatic steatosis in wild-type but not in apolipoprotein E knockout mice

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In a new study published in the peer-reviewed Science Signaling Journal , a team of researchers led by Professor Kezhong Zhang from the Center for Molecular Medicine and Genetics at Wayne State University School of Medicine, in collaboration with Associate Professor Brandon Davies from the University of Iowa and Associate Professor Ren Zhang from Wayne State University, has uncovered a critical pathway involving CREBH-C, a cleavage product of the CREBH protein, is processed and secreted by hepatocytes in response to energy demands and hepatic stress

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