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NRF1 and 2 promote the synthesis of mitochondrial proteins encoded in the nucleus, which are subsequently imported into mitochondria to sustain their proliferation and ensure quality control
It also helps protect mitochondria and reduces damage caused by chronic inflammation
Stimulates lipolysis (fat breakdown): AOD 9604, in particular, is noted for its ability to stimulate the breakdown of stored fat
The ESLD-associated cascade of inflammatory cytokine storms (Table 2), such as interleukin (IL)-6, IL-10, IL-8, IL-1, tumor necrosis factor alpha (TNF), fibrinogen-like protein 2, monocyte chemotactic protein 1, and interferon , promotes the occurrence of infection [10, 11]