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In the first case, this is due to the fact that NEM does not react with GSH under acidic conditions

Excitotoxicity and Its Role in Neurodegenerative Diseases Excitotoxicity, the process by which excessive excitatory neurotransmitter release (primarily glutamate) damages neurons, is a critical mechanism in many neurological disorders: Alzheimer's Disease: In Alzheimer's, the accumulation of amyloid-beta plaques triggers an inflammatory response that sensitizes neurons to glutamate toxicity

These endeavors aim to lay the necessary experimental groundwork for developing effective treatments

The results may reveal oral treatment with vitamin B12 to be, as Lederle [35] put it, medicines best kept secret

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