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Reactive Oxygen Species (ROS) are increased by the consumption of sugars and oxidized vegetable oils, smoking, alcohol, exposure to environmental toxins, high or chronic emotional stress, circadian rhythm dysregulation (poor sleep), lack of exercise, infections, and a lack of antioxidant intake

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Furthermore, the localised heat effects of laser exposure can augment the fluidity of stratum corneum lipids and facilitate regulated liposomal fusion and payload release, hence enhancing bioavailability and targeted accumulation of medicines