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Conclusion In this study, molecular docking, molecular dynamic simulation, QM/MM binding energy calculation and post simulation analysis has been carried out to seek detailed information of carmustine, SWCNT, GR system

So far, most of this data comes from animal studies or early-phase research, not large human trials

Multiple sequence alignment analyses revealed that GSTO1-1 and GSTO2-2 contain a conserved catalytic cysteine residue and GSH binding sites, while other classes of GSTs have different amino acids in these positions, explaining why only GSTOs show DHAR activity 10,13

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